学部・大学院区分理学部
時間割コード0681160
科目区分専門基礎科目
Basic Specialized Courses
科目名　【日本語】有機化学１
科目名　【英語】Organic Chemistry I
コースナンバリングコード
担当教員　【日本語】SHIN Jiyoung ○
担当教員　【英語】SHIN Jiyoung ○
単位数2
開講期・開講時間帯秋 水曜日 １時限
Fall Wed 1
授業形態講義
Lecture
学科・専攻
G30 Chemistry
必修・選択
* See "Remarks"


授業の目的　【日本語】
The main purpose of this course is to acquire a logical framework for understanding fundamental organic chemistry.
This framework emphasizes how the structures of organic molecules, as well as the electron density configurations, are related to patterns of chemical reactions.
授業の目的　【英語】
到達目標　【日本語】
On the basis of the knowledge educated following the course contents, the students will be able to solve progressive problems sequentially.
到達目標　【英語】
授業の内容や構成
Class 1. Structure Prospective of Organic Molecules --- Atomic Electron Configuration and Construction of Organic Molecules (Hybridization)
Class 2. Projection of Molecular Structures of Organic Molecules and Classification of the Isomers --- Constitutional (Chain, Position, and Functional Group) Isomers and Stereoisomers (Diastereomers and Enantiomers)
Class 3. Optical Activities of Stereoisomers and Assignment of Stereoisomeric Structures --- Fischer and Newman Projections; Absolute (R/S) and Optically Observed (D/L) Rotations; Specific Rotation and Enantiomeric Purity; Meso Compound
Class 4. Electron Density Configuration of Organic Molecules and Their Acidity/Basicity --- Formal Charges and Oxidation Sates; Acidity/Basicity and Electrophilicity/Nucleophilicity; Type of Chemical Reactions
Class 5. Potential Energy Profiles for Kinetically and Thermodynamically Favorable Reactions --- Stability of Carbocations, Carbanions, and Hydrocarbon Radicals and the Stabilization Factors (Hyperconjugation and Resonance)
Class 6. Assessment of the Classes 1-5 with Practice Problems
Class 7. General Trends of Aliphatic Nucleophilic Substitutions and Bimolecular Reactions (SN2) --- Efficient Substrates and Proper Leaving Groups; Reactivity of Nucleophiles and Solvent Effect; Stereochemistry; Competing Reactions
Class 8. Unimolecular Aliphatic Nucleophilic Substitutions (SN1) --- Efficient Substrates and Proper Leaving Groups; Nucleophilicity and Solvolysis; Stability of Carbocation Intermediate; Stereochemistry; Competing Reactions
Class 9. Aliphatic Eliminations --- Unimolecular (E1 and E1CB) and Bimolecular (E2) Elimination; Thermodynamically and Kinetically favored (Zaitsev and Hofmann) Eliminations
Class 10. Types of Nucleophiles and Haloalkanes and Their Reaction Trends/Overview (Substitutions & Eliminations)
Class 11. Assessment of the Classes 7-10 with Practice Problems
Class 12. Nomenclature of Organic Compounds --- Saturated/Unsaturated Hydrocarbons; Functional Groups; Aromatic Hydrocarbons; Stereochemical Assignments; Fused Rings (Spiroalkanes and Bicyclo/Tricycloalkanes)
Class 13. Structures and Stereochemistry of Cycloalkanes and their Stability and Reactivity
Class 14. Preparation of Haloalkanes (Radical Reactions) --- Potential Energy Profiles of Reaction Coordinates
Class 15. Assessment of Overall Classes with Practice Problems (1-14)
履修条件
Fundamentals of Chemistry I and II
関連する科目
Organic Chemistries 2, 3, 4, and 5
成績評価の方法と基準
Examination [Final (30%)] and Assignment of Homework (70%): S(x≧90), A(90>x≧80), B(80>x≧70), C(70>x≧60), and F(60>x). The condition was modified within the pandemic.
教科書・テキスト
Organic Chemistry: Structure and Function (Seventh Edition), Peter C. Vollhardt and Neil E. Schore, (W. H. Freeman and Company), New York, 2014, Chapters 1-7.
参考書
Organic Chemistry (second edition), Jonathan Clayden, Nick Greeves, and Stuart Warren (Oxford University Press), 2012 ISBN- 10:0199270295.
課外学習等（授業時間外学習の指示）
注意事項
他学科聴講の可否
他学科聴講の条件
レベル
キーワード
履修の際のアドバイス
授業開講形態等
遠隔授業（オンデマンド型）で行う場合の追加措置