| 授業の目的 【日本語】 | | Aim: This course aims to develop students foundation in Genetics, and is the beginning of a series of courses on Genetics.
Objectives: By the end of this course, students should be equipped with knowledge concerning the mechanisms of processes related to how genetic information is inherited rigidly and flexibly from generation to generation.
Students are expected to become confident at using appropriate scientific terminology, be able to understand and explain the studied genetics concepts, and be able to analytically manipulate this information.
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| 授業の目的 【英語】 | | |
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| 到達目標 【日本語】 | | | At the end of this course students will be able to clearly understand and explain in appropriate scientific terms DNA and chromosome structure, as well as the detailed mechanisms of DNA replication, DNA repair and DNA recombination. |
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| 到達目標 【英語】 | | |
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| 授業の内容や構成 | | 1. DNA and RNA structure
Students will learn about detailed polynucleotide structure ad its relation to genetic processes.
2. Chromosomes, chromatin, and the nucleosome
Students will learn how DNA is structurally organized in the cell and how this structure is dynamically maintained and altered throughout cells' life.
3. Replication of DNA
Students will learn the detailed mechanism of DNA replication, in both eukaryotic and prokaryotic cells.
4. Mutability and repair of DNA
Students will learn what causes changes in DNA and the cellular mechanisms for DNA repair.
5. Genetic recombination
Students will learn in depth about the different types of DNA recombination mechanisms, including examples of these mechanisms in eukaryotic and prokaryotic cells.
Instructions for out-of-class study: This course require students to prepare for each class in advance by reading the assigned material and summarizing it before class.
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| 履修条件 | | | Strongly recommended to have completed Fundamentals of Biology 1 |
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| 関連する科目 | | | Genetics II, Genetics III |
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| 成績評価の方法と基準 | | Evaluation is based on class participation, assignments and written examinations. A minimum score of 60/100 in every category is necessary to receive a passing grade.
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| 教科書・テキスト | | | Molecular Biology of the Gene, Watson, James D. et al., Pearson Education. |
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| 参考書 | | Essentials of Genetics, William S. Klug et al., Benjamin Cummings.
Molecular Biology of the Cell, B. Alberts et al., Taylor and Francis. |
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| 課外学習等（授業時間外学習の指示） | | |
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| 注意事項 | | | Please note that the class time will focus on discussion of the material, so it is essential that students come prepared. |
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| 遠隔授業（オンデマンド型）で行う場合の追加措置 | | |
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