学部・大学院区分

理学部

時間割コード

0681170

科目区分

専門科目
Specialized Courses

科目名　【日本語】

有機化学２

科目名　【英語】

Organic Chemistry II

コースナンバリングコード

担当教員　【日本語】

SHIN Jiyoung ○

担当教員　【英語】

SHIN Jiyoung ○

単位数

開講期・開講時間帯

春水曜日２時限
Spring Wed 2

授業形態

講義
Lecture

学科・専攻

G30 Chemistry

必修・選択

* See "Remarks"

授業の目的　【日本語】

The main purpose of this course is to acquire a logical framework for understanding fundamental organic chemistry. Many chemical reactions of organic compounds begin with nucleophile-electrophile interactions. This framework provides an influence for chemical reactions of the organic molecules having π-bonds.

授業の目的　【英語】

到達目標　【日本語】

On the basis of the knowledge, we consecutively learn how to solve practical problems in organic chemistry.

到達目標　【英語】

授業の内容や構成

Class 1. Electron Configuration of Unsaturated Hydrocarbons and Their Reaction Trends
--- Difference of Reactivity between Saturated and Unsaturated Aliphatic Hydrocarbons as well as Aromatic Hydrocarbons

Class 2. Nuclear Magnetic Resonance (NMR) Spectroscopy of Organic Molecules
--- Level of Energy Source for Various Spectroscopy; Larmor Frequency and Quantized Energy; Spin Spinning and Applied Magnetic Field; Zeeman Effect and Resonances; Shielding and Deshielding; Downfield and Upfield; Chemical Shifts, Integration, and Peak Splitting; [N+1] rule

Class 3. Preparations of Alkenes and Sequence of Electrophilic Additions of Alkenes
--- Potential Energy Stability of Unsaturated Aliphatic Compounds and Electrophilic Additions; Preparations by E2 Elimination and Dehydration; Hydrogenation; Halogenations (toward Monohaloalkane, Dihaloalkane, Halohydrin, and Allylic halide) of Simple Alkenes and Conjugated Dienes

Class 4. Electrophilic Additions of Alkenes
--- Hydration; Carbene Addition; Oxidation; Redical Addition; Heck Coupling; Polymerization

Class 5. Assessment of the Classes 1-4 with Practice Problems

Class 6. Reactions of delocalized pai-systems (Diels-Alder Reactions and Electrocyclization)
--- Efficient Dienes and Dienophiles; Stereochemistry in Diels-Alder Reactions (Endo/Exo cycloadditions and Endo Rule); Thermal and Photochemical Cyclization for Even- and Odd-Numbered Double Bonds

Class 7. Preparations of Alkynes and Sequence of Electrophilic Additions of Alkenes
--- Hydrogenation; Halogenation; Hydration

Class 8. Delocalized π-Systems and Reactivity of Benzene
--- Stability of Extended Conjugations and the Electron Configuration of Delocalized π-Systems (Nonaromatic/Aromatic/Antiaromatic Compounds); Projection of Resonances

Class 9. Reaction of Benzene --- Electrophilic Aromatic Substitutions (Halogenation, Nitration, Sulfonation, Friedel-Crafts Alkylation, Friedel-Crafts Acylation, Wolff-Kishner and Clemmensen Reductions)

Class 10. Assessment of he Classes 6-9 with Practice Problems

Class 11. Electrophilic Substitutions of Substituted Benzenes
--- ortho & para- and meta-Directing Groups and the Reactivities

Class 12. Nucleophilic Substitutions of Benzene (via Benzyne Formation or through Inductive Effects of Substituents)

Class 13. Preparations of Multiply Substituted Benzenes
--- Protection/Deprotection of amine; Reduction/Oxidation

Class 14. Electrophilic Substitutions of Fused Aromatic Compounds (Naphthalene and Antracene)

Class 15. Assessment of the Overall Classes (1-14) with Practice Problems

履修条件

Fundamental Chemistries I and II, Organic Chemistry I