学部・大学院区分
Undergraduate / Graduate

理学部

時間割コード
Registration Code

0681200

科目区分
Course Category

専門科目
Specialized Courses

科目名　【日本語】
Course Title

有機化学５

科目名　【英語】
Course Title

Organic Chemistry V

コースナンバリングコード
Course Numbering Code

担当教員　【日本語】
Instructor

SHIN Jiyoung ○

担当教員　【英語】
Instructor

SHIN Jiyoung ○

単位数
Credits

開講期・開講時間帯
Term / Day / Period

秋金曜日２時限
Fall Fri 2

授業形態
Course style

講義
Lecture

学科・専攻
Department / Program

G30 Chemistry

必修・選択
Compulsory / Selected

See "Course List and Graduation Requirements" for your program for your enrollment year.

授業の目的　【日本語】
Goals of the Course(JPN)

授業の目的　【英語】
Goals of the Course

The primary purpose of the course is to learn the spectroscopic analysis of organic molecules and the interpretation of spectral data. The course begins with theoretical/fundamental knowledge on the chromatographic and spectroscopic techniques (GC, HPLC, NMR, UV, IR, Raman, Mass, and so on) and continues to assignments of organic molecular structures with Spectra-type problems. Furthermore, it covers problem-solving regarding organic reactions to reinforce students’ understanding of molecular structures/reactivities.

到達目標　【日本語】
Objectives of the Course(JPN))

到達目標　【英語】
Objectives of the Course

The participants are expected to solve the progressive problems sequentially.

授業の内容や構成
Course Content / Plan

Class 1 & 2. Purification/Separation of Organic Molecules --- Chromatographic Principles and Methods; Gas Chromatography and Liquid Chromatography.
Class 3. Principle of Mass Spectrometry --- Ionization Techniques (EI, CI, FAB, ESI, APCI); Ion Separation Techniques (Magnetic Sector, Quadrupole, Ion Trap, TOF, FT); Fragmentations (Heterolytic and Homolytic Cleavages); Mass Patterns of Isotopes.
Class 4. Assignment of Mass Spectra --- Guidelines for predicting prominent EI Spectra peaks for Alcohols, Ethers, Ketones, Carboxylic Acids, Carboxylic Esters, Amines, and Aliphatic Sulfides.
Class 5. Vibration Spectroscopy --- FT-IR Absorption Spectroscopy and Raman Spectroscopy; Rayleigh and Stokes/Antistokes lines; Molecular Vibrational Motions; Assignment of IR Spectra of Organic Molecules.
Class 6. UV-Vis Absorption Spectroscopy --- Wavenumber & Wavelength; Map of UV/vis absorption spectrometer (Monochromator and Diode type); Beer-Lambert Law and Molecular Absorption Coefficient; Electron Transitions Involving p/s/n Electrons, Charge-Transfer Electrons, and d/f Electrons; pai-Conjugated Systems; Absorption in the Gaseous States.
Class 7. Emission Spectroscopy --- Jablonski Energy Diagram and Electron Spin States; Fluorescence and Phosphorescence; Stokes Shift; Instrumental Outlines; Lifetime Decay Profiles; Quantum Yield; Steady State & Transient Absorption Spectroscopy.
Class 8 & 9. Fundamental Principle of NMR Spectroscopy --- NMR Active/Inactive Nuclei; External Magnetic Field, Larmor Frequency, Resonance Feature, Saturation, and Net Magnetization, 90 Degree Pulse, Spin-Spin Decay, FT of FID, Structure of NMR Machine, Chemical Shift, Shielding/Deshielding, J coupling; Karplus Curve for Vicinal Couplings and Cis/Trans Correlation; Shimming; Probe Tuning; Locking; Important Parameters for NMR Analysis.
Class 10. Characterization of Molecular Structure and Assignment of NMR Spectra, and Advanced Techniques --- Peak Assignments of NMR Spectra of Example Organic Compounds (1H, COSY, NOESY, ROESY, APT 13C, HSQC, HMBC, TOCSY NMR Spectra); NMR Spectra of Paramagnetic Metal Complex.
Class 11. Students’ Presentation and Discussion (Assessment of the Classes 1-10).
Class 12. Problem-Solving Process for Structure Determination and the Corresponding Organic Reaction.
Class 13. Problem-Solving Process for Structure Determination and the Corresponding Organic Reaction.
Class 14. Problem-Solving Process for Structure Determination and the Corresponding Organic Reaction.
Class 15. Course Assessment and Solution Steps.

履修条件
Course Prerequisites

Organic chemistries I-II