学部・大学院区分
Undergraduate / Graduate
理学部
時間割コード
Registration Code
0681200
科目区分
Course Category
専門科目
Specialized Courses
科目名 【日本語】
Course Title
有機化学5
科目名 【英語】
Course Title
Organic Chemistry V
コースナンバリングコード
Course Numbering Code
担当教員 【日本語】
Instructor
SHIN Jiyoung ○
担当教員 【英語】
Instructor
SHIN Jiyoung ○
単位数
Credits
2
開講期・開講時間帯
Term / Day / Period
秋 金曜日 2時限
Fall Fri 2
授業形態
Course style
講義
Lecture
学科・専攻
Department / Program
G30 Chemistry
必修・選択
Compulsory / Selected
See "Course List and Graduation Requirements" for your program for your enrollment year.


授業の目的 【日本語】
Goals of the Course(JPN)
授業の目的 【英語】
Goals of the Course
The primary purpose of the course is to learn the spectroscopic analysis of organic molecules and the interpretation of spectral data. The course begins with theoretical/fundamental knowledge on the chromatographic and spectroscopic techniques (GC, HPLC, NMR, UV, IR, Raman, Mass, and so on) and continues to assignments of organic molecular structures with Spectra-type problems. Furthermore, it covers problem-solving regarding organic reactions to reinforce students’ understanding of molecular structures/reactivities.
到達目標 【日本語】
Objectives of the Course(JPN))
到達目標 【英語】
Objectives of the Course
The participants are expected to solve the progressive problems sequentially.
授業の内容や構成
Course Content / Plan
Class 1 & 2. Purification/Separation of Organic Molecules --- Chromatographic Principles and Methods; Gas Chromatography and Liquid Chromatography.
Class 3. Principle of Mass Spectrometry --- Ionization Techniques (EI, CI, FAB, ESI, APCI); Ion Separation Techniques (Magnetic Sector, Quadrupole, Ion Trap, TOF, FT); Fragmentations (Heterolytic and Homolytic Cleavages); Mass Patterns of Isotopes.
Class 4. Assignment of Mass Spectra --- Guidelines for predicting prominent EI Spectra peaks for Alcohols, Ethers, Ketones, Carboxylic Acids, Carboxylic Esters, Amines, and Aliphatic Sulfides.
Class 5. Vibration Spectroscopy --- FT-IR Absorption Spectroscopy and Raman Spectroscopy; Rayleigh and Stokes/Antistokes lines; Molecular Vibrational Motions; Assignment of IR Spectra of Organic Molecules.
Class 6. UV-Vis Absorption Spectroscopy --- Wavenumber & Wavelength; Map of UV/vis absorption spectrometer (Monochromator and Diode type); Beer-Lambert Law and Molecular Absorption Coefficient; Electron Transitions Involving p/s/n Electrons, Charge-Transfer Electrons, and d/f Electrons; pai-Conjugated Systems; Absorption in the Gaseous States.
Class 7. Emission Spectroscopy --- Jablonski Energy Diagram and Electron Spin States; Fluorescence and Phosphorescence; Stokes Shift; Instrumental Outlines; Lifetime Decay Profiles; Quantum Yield; Steady State & Transient Absorption Spectroscopy.
Class 8 & 9. Fundamental Principle of NMR Spectroscopy --- NMR Active/Inactive Nuclei; External Magnetic Field, Larmor Frequency, Resonance Feature, Saturation, and Net Magnetization, 90 Degree Pulse, Spin-Spin Decay, FT of FID, Structure of NMR Machine, Chemical Shift, Shielding/Deshielding, J coupling; Karplus Curve for Vicinal Couplings and Cis/Trans Correlation; Shimming; Probe Tuning; Locking; Important Parameters for NMR Analysis.
Class 10. Characterization of Molecular Structure and Assignment of NMR Spectra, and Advanced Techniques --- Peak Assignments of NMR Spectra of Example Organic Compounds (1H, COSY, NOESY, ROESY, APT 13C, HSQC, HMBC, TOCSY NMR Spectra); NMR Spectra of Paramagnetic Metal Complex.
Class 11. Students’ Presentation and Discussion (Assessment of the Classes 1-10).
Class 12. Problem-Solving Process for Structure Determination and the Corresponding Organic Reaction.
Class 13. Problem-Solving Process for Structure Determination and the Corresponding Organic Reaction.
Class 14. Problem-Solving Process for Structure Determination and the Corresponding Organic Reaction.
Class 15. Course Assessment and Solution Steps.
履修条件
Course Prerequisites
Organic chemistries I-II
関連する科目
Related Courses
Organic chemistries 2~4
成績評価の方法と基準
Course Evaluation Method and Criteria
Examination (final: 40%) and Presentation (30%) as well as Assessment of Homework (30%): Credits will be awarded to those students who score 60 or more.Grades are as follows: S(x90), A(90>x80), B(80>x70), C(70>x60), and F(60>x).This condition can be reconsidered following the pandemic condition.
不可(F)と欠席(W)の基準
Criteria for "Fail (F)" & "Absent (W)" grades
The student needs to contact the course instructor when the student wants to withdraw from the course. No submission of sickness/absence reports and lack of attendance score will result in an 'F' grade: It is for the protection of other attendances in the corresponding course from the frequent absences of the specific/uncertain student(s).
参考書
Reference Book
1. Spectrometric Identification of Organic Compounds (8th Edition), Robert M. Silverstein, Francis X. Webster, David J. Kiemle, and David L. Bryce, (Wiley), 2012, ISBN-10:0470616377.
2. Spectroscopic Methods in Organic Chemistry (2nd Edition) Manfred Hesse, Herbert Meier, Bernd Zeeh (Translated by Richard Dunmur, Martin Myrray), Thieme, New York, ISBN 978-1-58890-488-1.
教科書・テキスト
Textbook
Organic Chemistry: Structure and Function (Seventh Edition), Peter C. Vollhardt and Neil E. Schore, (W. H. Freeman and Company), New York, 2014, Chapters 10-21. - Handout materials of the lectures will be given in the respective classes.
課外学習等(授業時間外学習の指示)
Study Load(Self-directed Learning Outside Course Hours)
Students are recommended to review the lectures by solving the related homework questions. Each assignment is due by the start of the next class if it is not specially announced.
注意事項
Notice for Students
Submission of "Course Withdrawal Request Form is necessary to withdraw the course. The student needs to contact the course instructor when the student wants to withdraw from the course. No submission of sickness/absence reports and lack of attendance score will result in an 'F' grade: It is for the protection of other attendances in the corresponding course from the frequent absences of the specific/uncertain student(s).
他学科聴講の可否
Propriety of Other department student's attendance
Chemistry students are the majority. The course participants should have completed the fundamentals of chemistry 1 and 2 as well as organic chemistry 1, 2, and 3.
他学科聴講の条件
Conditions for Other department student's attendance
レベル
Level
3rd-grade undergraduate students take the course in principle.
キーワード
Keyword
履修の際のアドバイス
Advice
授業開講形態等
Lecture format, etc.
Each lecture is provided in a PowerPoint projection. Participants will obtain lecture materials corresponding to each class through NUCT. Also, sudden questions will be given to students during lectures to provide substantial feedback.
遠隔授業(オンデマンド型)で行う場合の追加措置
Additional measures for remote class (on-demand class)