授業の目的 【日本語】 Goals of the Course(JPN) | | データサイエンス特別講義1,2,3を基礎とし,トランスクリプトミクスの実際,プロテオミクスやメタボロミクスを含めたマルチオミクスの概要を学ぶ. |
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授業の目的 【英語】 Goals of the Course | | Based on Data Sciences 1, 2 and 3, this course introduces practical approaches of transcriptomics and outline of multi-omics including proteomics and metabolomics. |
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到達目標 【日本語】 Objectives of the Course(JPN) | | Based on Data Sciences 1, 2 and 3, in this course, students get knowledge of practical approaches of transcriptomics and outline of multi-omics including proteomics and metabolomics. |
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到達目標【英語】 Objectives of the Course | | |
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授業の内容や構成 Course Content / Plan | | 1. Preparing a computing environment for NGS analysis in Windows/Mac (Instructions for Windows Subsystem for Linux 2; Instructions for homebrew/Bioconda to install popular bioinformatics tools; Instructions for downloading NGS data from Sequence Read Archive)
2. Guidance for RNA-Seq data analysis pipelines (Read mapping, calculation of the expression values and statistical analysis)
3. Genome-wide analysis of binding sites of a DNA-binding transcription factor (Mapping, Peak detection and Identification of promoter regulated by the target transcription factor)
4. Integrated data mining with biological big data using R (Correlation analysis and Clustering)
5. 16S rDNA metagenome analysis using bioinformatics tools (LocalBLAST and QIIME2)
6. Outline of proteomics and metabolomics
7. Application of multi-omics
1. Preparing a computing environment for NGS analysis in Mac (Instructions for homebrew/Bioconda to install popular bioinformatics tools; Instructions for downloading NGS data from Sequence Read Archive)
2. Guidance for RNA-Seq data analysis pipelines (Read mapping, calculation of the expression values and statistical analysis)
3. Genome-wide analysis of binding sites of a DNA-binding transcription factor (Mapping, Peak detection and Identification of promoter regulated by the target transcription factor)
4. Integrated data mining with biological big data using R (Correlation analysis and Clustering)
5. 16S rDNA metagenome analysis using bioinformatics tools (LocalBLAST and QIIME2)
6. Outline of proteomics and metabolomics
7. Application of multi-omics |
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履修条件・関連する科目 Course Prerequisites and Related Courses | | |
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成績評価の方法と基準 Course Evaluation Method and Criteria | | Evaluate each lesson by attendance and short report. |
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教科書・テキスト Textbook | | |
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参考書 Reference Book | | |
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課外学習等(授業時間外学習の指示) Study Load(Self-directed Learning Outside Course Hours) | | After lecture, students should learn about practice of omics study by reading scientific papers and by accessing to webtools for omics study. |
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使用言語 Language Used in the Course | | |
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授業開講形態等 Lecture format, etc. | | |
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遠隔授業(オンデマンド型)で行う場合の追加措置 Additional measures for remote class (on-demand class) | | |
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