学部・大学院区分
Undergraduate / Graduate

理・博前

時間割コード
Registration Code

2683522

科目区分
Course Category

前期専門科目
MC Specialized Course

科目名　【日本語】
Course Title

[G30] 生命科学特別講義２

科目名　【英語】
Course Title

[G30] Special Lectures of Biological Science 2

コースナンバリングコード
Course Numbering Code

担当教員　【日本語】
Instructor

小嶋　誠司 ○ 岡本　浩二

担当教員　【英語】
Instructor

KOJIMA Seiji ○ OKAMOTO koji

単位数
Credits

開講期・開講時間帯
Term / Day / Period

秋集中その他その他
Intensive(Fall) Other Other

授業形態
Course style

学科・専攻
Department / Program

理学専攻

必修・選択
Required / Selected

Elective

授業の目的　【日本語】
Goals of the Course(JPN)

授業の目的　【英語】
Goals of the Course

Mitochondria, major organelles in the eukaryotic cell, will be focused in this course. Cutting-edge findings on their basic structures, functions, and dynamics, which have not yet been described in the biology textbooks, will be introduced. This course will aim to help students create their own concept on "what is life?".

到達目標　【日本語】
Objectives of the Course(JPN))

到達目標　【英語】
Objectives of the Course

Students will be able to obtain the understanding of mitochondria as key players governing life and death, and as multifaceted platforms regulating higher-order biological functions, towards applying these knowledges to establishment of human health and longevity.

授業の内容や構成
Course Content / Plan

Lecture-1 (Energy conversion and heat generation): Coupling and uncoupling of electron transport and oxidative phosphorylation in the mitochondrial inner membrane

Lecture-2 (Protein import and lipid transfer): Translocators and carriers for mitochondria-destined proteins and phospholipids

Lecture-3 (Fission, fusion, and transport): GTP-driven mechanochemical enzymes and molecular switches regulating mitochondrial shaping and motility

Lecture-4 (Stress response and signaling): Cell autonomous and non-autonomous mechanisms for bidirectional crosstalk between mitochondria and the nucleus

Department seminar (Quality and quantity control): Autophagy-mediated selective clearance of dysfunctional and superfluous mitochondria

履修条件
Course Prerequisites

Not required