授業の目的 【日本語】
Goals of the Course(JPN) | | | This course deals with the central nervous system that controls reproduction in mammals. It also introduces roles and interactions of physiologically active substances including hormones, neurotransmitters, neuropeptides, growth factors, and cytokines. |
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授業の目的 【英語】
Goals of the Course | | | This course deals with the central nervous system that controls reproduction in mammals. It also introduces roles and interactions of physiologically active substances including hormones, neurotransmitters, neuropeptides, growth factors, and cytokines. |
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到達目標 【日本語】
Objectives of the Course(JPN) | | | The goals of this course are to be able to understand and discuss the basics of molecular, cellular and medical neurobiology. |
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到達目標【英語】
Objectives of the Course | | | The goals of this course are to be able to understand and discuss the basics of molecular, cellular and medical neurobiology. |
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授業の内容や構成
Course Content / Plan | | 1. Introduction
2. Cell Biology of the Nervous System，Cell Membrane Structure and Functions, Membrane Transport
3. Electrical Excitability and Ion Channels, Lipids, The Cytoskeleton of Neurons and Glia
4. Intracellular Trafficking, Axonal Transport, Cell Adhesion Molecules
5. Myelin Structure and Biochemistry, Energy Metabolism and Brain, Synaptic Transmission and Cellular Signaling
6. Acetylcholine, Catecholamine, Serotonin
7. Histamine, Glutamate and Glutamate receptors, GABA
8. Purinergic Signaling, Peptides, G Protein
9. Cyclic Nucleotides in the Nervous System, Phosphoinositides, Calcium
10. Serine and Threonine Phosphorylation, Tyrosine Phosphorylation, Transcription Factors in the Central Nervous System
11. Development of the Nervous System Growth factors, Stem Cells in the Nervous System
12. Formation and Maintenance of Myelin, Axonal Growth in the Adult Mammalian Nervous System: Regeneration and Compensatory Plasticity, Molecular Mechanisms and Consequences of Immune and Nervous System Interactions
13. Neuroinflammation, Brain Ischemia and Reperfusion: Cellular and Molecular Mechanisms in Stoke Injury, Lipid Mediators: Eicosanoids, Docosanoids and Platelet-Activating Factor
14. Apoptosis and Necrosis, Endocrine Effect on the Brain and Their Relationship to Behavior, The Neurochemistry of Sleep and Wakefulness
15. Discussion and Remarks |
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履修条件・関連する科目
Course Prerequisites and Related Courses | | |
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成績評価の方法と基準
Course Evaluation Method and Criteria | | | Evaluation will be based on class attendance and attitude in class (40%), presentation (30%) and discussion (30%). If you miss this class more than 30%, I evaluate your grades as 'absence'. |
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教科書・テキスト
Textbook | | | Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, eighth edition, Academic Press-Elsevier |
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参考書
Reference Book | | | Will be introduced in the class. |
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課外学習等（授業時間外学習の指示）
Study Load(Self-directed Learning Outside Course Hours) | | | Students will be assigned several chapters on the textbook written in English for summarization. Reading through entire chapters on the textbook is also required. |
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使用言語
Language Used in the Course | | |
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授業開講形態等
Lecture format, etc. | | |
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遠隔授業（オンデマンド型）で行う場合の追加措置
Additional measures for remote class (on-demand class) | | |
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