学部・大学院区分
Undergraduate / Graduate
理学部
時間割コード
Registration Code
0681160
科目区分
Course Category
専門基礎科目
Basic Specialized Courses
科目名 【日本語】
Course Title
有機化学1
科目名 【英語】
Course Title
Organic Chemistry I
コースナンバリングコード
Course Numbering Code
担当教員 【日本語】
Instructor
SHIN Jiyoung ○
担当教員 【英語】
Instructor
SHIN Jiyoung ○
単位数
Credits
2
開講期・開講時間帯
Term / Day / Period
秋 水曜日 1時限
Fall Wed 1
授業形態
Course style
講義
Lecture
学科・専攻
Department / Program
Chemistry Biology / Science
必修・選択
Compulsory / Selected
Compulsory


授業の目的 【日本語】
Goals of the Course(JPN)
このコースは、入門的な有機化学の理解を促進し、学生が基本的な有機化学を理解するための論理的なフレームワークを構築するのに役立つように開設されました。このコースの主な目的は、学生が基本的な有機化学を理解するための論理的なフレームワークを構築できるようになる事です。 このコースでは、有機分子構造と電子密度組成が有機化学反応のパターンにどのように関連しているかを強調します。 コースの内容から学んだ知識に基づいて、分子内または分子間有機反応のメカニズムを調査し、進行性反応シーケンスの問題を解決することができます。
授業の目的 【英語】
Goals of the Course
This course was designed to promote an understanding of introductory organic chemistry and to help students build a logical framework for understanding fundamental organic chemistry. The primary purpose of this course is to help students build a logical framework for understanding fundamental organic chemistry. The course emphasizes how the organic molecular structures and the electron density compositions are related to patterns of organic chemical reactions. Participants are expected to investigate the mechanism of intramolecular or intermolecular organic reactions and solve the problem of progressive reaction sequences based on the knowledge learned through the course contents.
到達目標 【日本語】
Objectives of the Course(JPN))
このコースの主な目的は、学生が基本的な有機化学を理解するための論理的な枠組みを構築できるようにすることです。 有機化学1では、原子の電子配置や混成や軌道間相互作用による様々な分子構造の構築から始まり、分子の電子密度組成や分布を取り入れて各分子を安定化させる化学反応へと進みます。 古典的な反応メカニズムに関する実践的な演習により、学生は分子内または分子間で進行する古典的な反応機構に現れた特定のパターンを分別でき、最後にコースの内容で学んだ知識に基づいて、さまざまな進行性反応機構の問題を解決できます。学生は、コース内容から習得した知識に基づいて、有機分子間または有機分子内で起こる古典的な化学反応の個別反応機構を理解し、より複雑な有機反応機構に関する問題を解決することが期待されます。
到達目標 【英語】
Objectives of the Course
The primary purpose of this course is to help students build a logical framework for comprehending fundamental organic chemistry. Organic chemistry 1 begins with the electron configuration of atoms and the construction of various molecular structures by hybridization and inter-orbital interactions and continues to the chemical reactions that stabilize each molecule by incorporating the electron density composition and distribution of molecules. Hands-on exercises on classical reaction mechanisms enable students to discern classical reaction mechanisms and specific patterns proceeding within or between molecules. Finally, students can solve various progressive reaction sequence problems based on the knowledge learned in the course contents.
Students enable to indicate each mechanism of intermolecular or intramolecular organic reactions for aliphatic molecules and to solve problems of progressive reaction mechanisms based on the knowledge grasped from the course contents.
授業の内容や構成
Course Content / Plan
Class 1: Structure perspective of organic molecules: Atomic electron configuration and construction of organic molecules (hybridization).
Class 2: Structure projection of organic molecules and classification of isomers: Constitutional isomers and stereoisomers.
Class 3: Optical activities of stereoisomers and assignment of stereoisomeric structures: Absolute configurations and optically observed rotations, specific ration, and enantiomeric purity.
Class 4: Electron density configurations of organic molecules, inducing acidity and basicity: Formal charges and oxidation states, chemical reaction patterns.
Class 5: Potential energy profiles for kinetically and thermodynamically proceeding reactions: Stability of reaction intermediate and factor to stabilize carbocations, hydrocarbon radicals.
Class 6: Assessment of classes 1~5 with solving exercise problems.
Class 7: General trends of bimolecular aliphatic nucleophilic substitutions (SN2): Efficient substrates, leaving groups, nucleophiles, and solvents; Stereochemistry and competing reactions of SN2.
Class 8: Unimolecular aliphatic nucleophilic substitutions (SN1): Effective substrates, leaving group, nucleophiles, and solvents; Stereochemistry and competing reactions of SN1.
Class 9: Aliphatic Eliminations: Unimolecular (E1 and E1CB) and bimolecular (E2) eliminations, thermodynamically vs. thermodynamically favored eliminations.
Class 10: Identification and proper assignment for SN1, SN2, E1, and E2.
Class 11: Assessment of classes 7~10 with solving exercise problems.
Class 12: Nomenclature of organic compounds.
Class 13: Cycloalkanes: Structures, stereochemistry, stability, and reactivities.
Class 14: Radical reactions (preparation of haloalkanes): Potential energy profiles in reaction coordinations.
Class 15: Assessment of entire classes (classes 1~14) by solving exercise problems.
履修条件
Course Prerequisites
Fundamentals of Chemistry I and II
関連する科目
Related Courses
Organic Chemistry II, III, IV, and V
成績評価の方法と基準
Course Evaluation Method and Criteria
Examination [total 70%: two midterms (20% for each) and one final (30%)] and Assignment of Homework and Attendances (30%): S(x≧90), A(90>x≧80), B(80>x≧70), C(70>x≧60), and F(60>x) for the students who entered earlier than 2020; A+(≧95), A(95>x≧x80), B(80>x≧70), C(70>x≧65), C-(65>x≧60), and F(60>x) for the students who entered in 2020 or later than 2020.
不可(F)と欠席(W)の基準
Criteria for "Fail (F)" & "Absent (W)" grades
No submission of sickness/absence reports and lack of attendance score will result in an 'F' grade: It is for the protection of other attendances in the corresponding course from the frequent absences of the specific/uncertain student(s).
Students are recommended to prepare each lecture by reading the corresponding chapter in the textbook and to review it by solving the related homework questions. Each assignment should be submitted at the beginning of the next class. Late or no assignment submission is the deduction point of the grade.
参考書
Reference Book
Organic Chemistry (eighth edition, Global edition), Paula Yurkanis Bruice (Pearson), 2017 ISBN 10: 1-292-16034-9
教科書・テキスト
Textbook
Organic Chemistry: Structure and Function (Eighth Edition), Peter K. Vollhardt and Neil Schore, (W. H. Freeman and Company), New York, 2018, Chapters 1-7.
課外学習等(授業時間外学習の指示)
Study Load(Self-directed Learning Outside Course Hours)
Students are recommended to prepare each lecture by reading the corresponding chapters in the textbook and reviewing it by solving the related homework questions. NU general guideline considers the necessity of the average of 2~3 hours of personal study time per week for each credit.
注意事項
Notice for Students
Each homework is vital for reviewing the corresponding class, whose submission is strongly encouraged before the beginning of the next lesson. Late or no assignment submission is the deduction point of the grade.
他学科聴講の可否
Propriety of Other department student's attendance
他学科聴講の条件
Conditions for Other department student's attendance
レベル
Level
キーワード
Keyword
履修の際のアドバイス
Advice
授業開講形態等
Lecture format, etc.
Face-to-face course(Only face-to-face classes)
遠隔授業(オンデマンド型)で行う場合の追加措置
Additional measures for remote class (on-demand class)