学部・大学院区分
Undergraduate / Graduate | | 理学部 | | 時間割コード
Registration Code | | 0681200 | | 科目区分
Course Category | | 専門科目
Specialized Courses | | 科目名 【日本語】
Course Title | | 有機化学５ | | 科目名 【英語】
Course Title | | Organic Chemistry V | | コースナンバリングコード
Course Numbering Code | | | | 担当教員 【日本語】
Instructor | | SHIN Jiyoung ○ | | 担当教員 【英語】
Instructor | | SHIN Jiyoung ○ | | 単位数
Credits | | 2 | | 開講期・開講時間帯
Term / Day / Period | | 秋 金曜日 ２時限
Fall Fri 2 | | 授業形態
Course style | | 講義
Lecture | | 学科・専攻
Department / Program | | | | 必修・選択
Compulsory / Selected | | | |
授業の目的 【日本語】
Goals of the Course(JPN) | | | このコースは、有機分子の分光分析とスペクトルデータの解釈方を学ぶために開設されました。このコースは、クロマトグラフィーおよび分光技術（GC、HPLC、NMR、UV、IR、ラマン、マス分析など）に関する理論的/基本的な知識から始まります。コースの主な目的は、有機分子の分光分析とスペクトルデータの解釈を学ぶことです。 分子構造/反応性に対する理解を強化することで学生はスペクトルに関する問題を伴う有機分子構造の割り当てと有機反応に関する問題解決ができるようになります。 |
| | 授業の目的 【英語】
Goals of the Course | | | This course was established to learn spectroscopic analysis of organic molecules and how to interpret spectral data. The course begins with theoretical/fundamental knowledge on the chromatographic and spectroscopic techniques (GC, HPLC, NMR, UV, IR, Raman, Mass, and so on) and continues to assignments of organic molecular structures with Spectra-type problems. Furthermore, it covers problem-solving regarding organic reactions to reinforce students’ understanding of molecular structures/reactivities. The participants are expected to solve the progressive problems sequentially. |
| | 到達目標 【日本語】
Objectives of the Course(JPN)) | | | このコースは、有機分子の分光分析とスペクトルデータの解釈方を学ぶために開設されました。このコースは、クロマトグラフィーおよび分光技術（GC、HPLC、NMR、UV、IR、ラマン、マス分析など）に関する理論的/基本的な知識から始まります。コースの主な目的は、有機分子の分光分析とスペクトルデータの解釈を学ぶことです。 分子構造/反応性に対する理解を強化することで学生はスペクトルに関する問題を伴う有機分子構造の割り当てと有機反応に関する問題解決ができるようになります。 |
| | 到達目標 【英語】
Objectives of the Course | | | This course was established to learn spectroscopic analysis of organic molecules and how to interpret spectral data. The course begins with theoretical/fundamental knowledge on the chromatographic and spectroscopic techniques (GC, HPLC, NMR, UV, IR, Raman, Mass, and so on) and continues to assignments of organic molecular structures with Spectra-type problems. Furthermore, it covers problem-solving regarding organic reactions to reinforce students’ understanding of molecular structures/reactivities. The participants are expected to solve the progressive problems sequentially. |
| | 授業の内容や構成
Course Content / Plan | | Class 1 & 2. Purification/Separation of Organic Molecules --- Chromatographic Principles and Methods; Gas Chromatography and Liquid Chromatography.
Class 3. Principle of Mass Spectrometry --- Ionization Techniques (EI, CI, FAB, ESI, APCI); Ion Separation Techniques (Magnetic Sector, Quadrupole, Ion Trap, TOF, FT); Fragmentations (Heterolytic and Homolytic Cleavages); Mass Patterns of Isotopes.
Class 4. Assignment of Mass Spectra --- Guidelines for predicting prominent EI Spectral peaks for Alcohols, Ethers, Ketones, Carboxylic Acids, Esters, Amines, and Aliphatic Sulfides.
Class 5. Vibration Spectroscopy --- FT-IR Absorption Spectroscopy and Raman Spectroscopy; Rayleigh and Stokes/Antistokes lines; Molecular Vibrational Motions; Assignment of IR Spectra of Organic Molecules.
Class 6. UV-Vis Absorption Spectroscopy --- Wavenumber & Wavelength; Map of UV/vis absorption spectrometer (Monochromator and Diode-type); Beer-Lambert Law and Molecular Absorption Coefficient; Electron Transitions Involving p/s/n Electrons, Charge-Transfer Electrons, and d/f Electrons; pai-Conjugated Systems; Absorption in the Gaseous States.
Class 7. Emission Spectroscopy --- Jablonski Energy Diagram and Electron Spin States; Fluorescence and Phosphorescence; Stokes Shift; Instrumental Outlines; Lifetime Decay Profiles; Quantum Yield; Steady State & Transient Absorption Spectroscopy.
Class 8 & 9. Fundamental Principle of NMR Spectroscopy --- NMR Active/Inactive Nuclei; External Magnetic Field, Larmor Frequency, Resonance Feature, Saturation, and Net Magnetization, 90 Degree Pulse, Spin-Spin Decay, FT of FID, Structure of NMR Machine, Chemical Shift, Shielding/Deshielding, J coupling; Karplus Curve for Vicinal Couplings and Cis/Trans Correlation; Shimming; Probe Tuning; Locking; Important Parameters for NMR Analysis.
Class 10. Characterization of Molecular Structure and Assignment of NMR Spectra, and Advanced Techniques --- Peak Assignments of NMR Spectra of Example Organic Compounds (1H, COSY, NOESY, ROESY, APT 13C, HSQC, HMBC, TOCSY NMR Spectra); NMR Spectra of Paramagnetic Metal Complex.
Class 11. Students’ Presentation and Discussion (Assessment of the Classes 1-10).
Classes 12-14. Problem-Solving Process for Structure Determination and the Corresponding Organic Reaction.
Class 15. Course Assessment and Solution Steps. |
| | 履修条件
Course Prerequisites | | | Organic chemistry I and II |
| | 関連する科目
Related Courses | | | Organic Chemistry I~IV, Analytical Chemistry, Quantum Chemistry, Student Laboratory |
| | 成績評価の方法と基準
Course Evaluation Method and Criteria | | | Examination [total 70%: midterm (30%) and final (40%)] and Assessment of Homework and attendances (30%): S(x90), A(90>x80), B(80>x70), C(70>x60), and F(60>x) for the students who entered earlier than 2020; A+(95), A(95>xx80), B(80>x70), C(70>x65), C-(65>x60), and F(60x) for the students who entered in 2020 or later than 2020. |
| | 不可(F)と欠席(W)の基準
Criteria for "Fail (F)" & "Absent (W)" grades | | | The student needs to contact the course instructor when the student wants to withdraw from the course. In the cases of any unavoidable reasons such as sickness, accident, or no attendance school, the student may get a grade of 'Absent' through the judgment of the course instructor and the student when the student submits a 'Course Withdrawal Request Form' to receive the 'Absent' grade. No submission of sickness/absence reports and lack of attendance score will result in an 'F' grade: It is for the protection of other attendances in the corresponding course from the frequent absences of the specific/uncertain student(s). |
| | 参考書
Reference Book | | 1. Spectrometric Identification of Organic Compounds (8th Edition), Robert M. Silverstein, Francis X. Webster, David J. Kiemle, and David L. Bryce, (Wiley), 2012, ISBN-10:0470616377.
2. Spectroscopic Methods in Organic Chemistry (2nd Edition) Manfred Hesse, Herbert Meier, Bernd Zeeh (Translated by Richard Dunmur, Martin Myrray), Thieme, New York, ISBN 978-1-58890-488-1. |
| | 教科書・テキスト
Textbook | | - Organic Chemistry: Structure and Function (Eighth Edition), Peter K. Vollhardt and Neil Schore, (W. H. Freeman and Company), New York, 2018, Chapters 10-21.
- Handout materials of the lectures will be given in the respective classes. |
| | 課外学習等（授業時間外学習の指示）
Study Load(Self-directed Learning Outside Course Hours) | | | Students are recommended to review the lectures by solving the related homework questions. Each assignment is due by the start of the next class if it is not specially announced. Late or no assignment submission is the deduction point of the grade. NU general guideline considers the necessity of the average of 2~3 hours of personal study time per week for each credit. |
| | 注意事項
Notice for Students | | | | 他学科聴講の可否
Propriety of Other department student's attendance | | | | 他学科聴講の条件
Conditions for Other department student's attendance | | | | レベル
Level | | | | キーワード
Keyword | | | | 履修の際のアドバイス
Advice | | | | 授業開講形態等
Lecture format, etc. | | | Face-to-face course（Only face-to-face classes） |
| | 遠隔授業（オンデマンド型）で行う場合の追加措置
Additional measures for remote class (on-demand class) | | | |
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