学部・大学院区分
Undergraduate / Graduate | | 理学部 | | 時間割コード
Registration Code | | 0681200 | | 科目区分
Course Category | | 専門科目
Specialized Courses | | 科目名 【日本語】
Course Title | | [G30] 有機化学５ | | 科目名 【英語】
Course Title | | [G30] Organic Chemistry V | | コースナンバリングコード
Course Numbering Code | | | | 担当教員 【日本語】
Instructor | | SHIN Jiyoung ○ | | 担当教員 【英語】
Instructor | | SHIN Jiyoung ○ | | 単位数
Credits | | 2 | | 開講期・開講時間帯
Term / Day / Period | | 秋 金曜日 ２時限
Fall Fri 2 | | 授業形態
Course style | | 講義
Lecture | | 学科・専攻
Department / Program | | | School of Science・G30 Chemistry Program |
| | 必修・選択
Compulsory / Selected | | | See the “Course List and Graduation Requirements for your program for your enrollment year. |
| |
授業の目的 【日本語】
Goals of the Course(JPN) | | | この授業は、有機分子の分光分析およびスペクトルデータの解釈方法と、クロマトグラフィーおよび分光学的分析（GC、HPLC、NMR、UV、IR、ラマン、質量分析など）の理論/基礎知識について学ぶことを目的とします。有機分子の分光分析とスペクトルデータの解釈を学ぶことで、分子構造/反応性に対する理解度を強化します。有機分子構造の割り当てと有機反応に関する問題解決が可能となります。 |
| | 授業の目的 【英語】
Goals of the Course | | | The course aims to learn various spectroscopic analyses for organic molecules and the interpretation of spectral data. The course covers theoretical knowledge of chromatographic and spectroscopic techniques (GC, HPLC, NMR, UV, IR, Raman, mass spectrometry, etc.). The main objective is to learn how to assign spectral data of organic molecules properly, thus enabling correct identifications of organic molecular structures based on the related organic reactions. |
| | 到達目標 【日本語】
Objectives of the Course(JPN)) | | | 有機分子の分光分析とスペクトルデータの解釈方を学ぶことで、有機分子の分光分析とスペクトルデータの解釈や有機分子構造及びその化学反応性の有効な理解力を強化することで、スペクトルに関する問題に限りなく有機分子構造とその有機化学反応及び化学反応性に関するトータル問題解決も可能とします。最終的には学生さんの実際的な研究能力を高めます。 |
| | 到達目標 【英語】
Objectives of the Course | | | This course is designed to grasp the appropriate skills to interpret spectroscopic and spectral data of organic molecules and the theory/fundamentals of chromatographic and spectroscopic analyses (GC, HPLC, NMR, UV, IR, Raman, mass spectrometry, etc.). Students will understand sufficiently the molecular structure/reactivity in learning spectroscopic analysis and spectral data interpretation of organic molecules, enabling them to assign organic molecular structures, solve more practical questions on organic reactions, and advance to the actual research. |
| | 授業の内容や構成
Course Content / Plan | | Class 1 & 2. Purification/Separation of Organic Molecules --- Chromatographic Principles and Methods; Gas Chromatography and Liquid Chromatography.
Class 3. Principle of Mass Spectrometry --- Ionization Techniques (EI, CI, FAB, ESI, APCI); Ion Separation Techniques (Magnetic Sector, Quadrupole, Ion Trap, TOF, FT); Fragmentations (Heterolytic and Homolytic Cleavages); Mass Patterns of Isotopes.
Class 4. Assignment of Mass Spectra --- Guidelines for predicting prominent EI Spectral peaks for Alcohols, Ethers, Ketones, Carboxylic Acids, Esters, Amines, and Aliphatic Sulfides.
Class 5. Vibration Spectroscopy --- FT-IR Absorption Spectroscopy and Raman Spectroscopy; Rayleigh and Stokes/Antistokes lines; Molecular Vibrational Motions; Assignment of IR Spectra of Organic Molecules.
Class 6. UV-Vis Absorption Spectroscopy --- Wavenumber & Wavelength; Map of UV/vis absorption spectrometer (Monochromator and Diode-type); Beer-Lambert Law and Molecular Absorption Coefficient; Electron Transitions Involving p/s/n Electrons, Charge-Transfer Electrons, and d/f Electrons; pai-Conjugated Systems; Absorption in the Gaseous States.
Class 7. Emission Spectroscopy --- Jablonski Energy Diagram and Electron Spin States; Fluorescence and Phosphorescence; Stokes Shift; Instrumental Outlines; Lifetime Decay Profiles; Quantum Yield; Steady State & Transient Absorption Spectroscopy.
Class 8 & 9. Fundamental Principle of NMR Spectroscopy --- NMR Active/Inactive Nuclei; External Magnetic Field, Larmor Frequency, Resonance Feature, Saturation, and Net Magnetization, 90 Degree Pulse, Spin-Spin Decay, FT of FID, Structure of NMR Machine, Chemical Shift, Shielding/Deshielding, J coupling; Karplus Curve for Vicinal Couplings and Cis/Trans Correlation; Shimming; Probe Tuning; Locking; Important Parameters for NMR Analysis.
Class 10. Students’ Presentation and Discussion (Assessment of the Classes 1-10).
Class 11. Characterization of Molecular Structure and Assignment of NMR Spectra, and Advanced Techniques --- Peak Assignments of NMR Spectra of Example Organic Compounds (1H, COSY, NOESY, ROESY, APT 13C, HSQC, HMBC, TOCSY NMR Spectra); NMR Spectra of Paramagnetic Metal Complex.
Classes 12-14. Problem-Solving Process for Structure Determination and the Corresponding Organic Reaction.
Class 15. Course Assessment and Solution Steps. |
| | 履修条件
Course Prerequisites | | | Students should complete Organic Chemistries I and II, at least, as the prerequisite subjects. |
| | 関連する科目
Related Courses | | | Graduation Research, Structural Chemistry, Analytical Mechanics, Chemistry Laboratory. |
| | 成績評価の方法と基準
Course Evaluation Method and Criteria | | | Examination [total 70%: midterm (30%) and final (40%)] and Assessment of Homework and attendances (30%): A+(≧95), A(95>x≧x80), B(80>x≧70), C(70>x≧65), C-(65>x≧60), and F(60＞x). |
| | 不可(F)と欠席(W)の基準
Criteria for "Fail (F)" & "Absent (W)" grades | | In the cases of any unavoidable reasons such as sickness, accident, or no attendance to school, the student may get a grade of 'Absent' through the judgment of the course instructor and the student when the student submits a 'Course Withdrawal Request Form' to receive the 'Absent' grade.
No submission of sickness/absence reports and lack of attendance score will result in an 'F' grade: It is for the protection of other attendances in the corresponding course from the frequent absences of the specific/uncertain student(s). |
| | 参考書
Reference Book | | 1. Organic Chemistry (Eighth edition, Global edition), Paula Yurkanis Bruce, 2017, ISBN 10: 1-292-16034-9, Chapters 13-14.
2. Spectrometric Identification of Organic Compounds (8th Edition), Robert M. Silverstein, Francis X. Webster, David J. Kiemle, and David L. Bryce, (Wiley), 2012, ISBN-10:0470616377.
3. Spectroscopic Methods in Organic Chemistry (2nd Edition) Manfred Hesse, Herbert Meier, Bernd Zeeh (Translated by Richard Dunmur, Martin Myrray), Thieme, New York, ISBN 978-1-58890-488-1. |
| | 教科書・テキスト
Textbook | | - Organic Chemistry: Structure and Function (Eighth Edition), Peter K. Vollhardt and Neil Schore, (W. H. Freeman and Company), New York, 2018, Chapters 10-21.
- Handout materials of the lectures will be given in the respective classes. |
| | 課外学習等（授業時間外学習の指示）
Study Load(Self-directed Learning Outside Course Hours) | | | Students are recommended to review the lectures by solving the related homework questions. NU general guideline considers the necessity of the average of 2~3 hours of personal study time per week for each credit. |
| | 注意事項
Notice for Students | | | Students are recommended to review the lectures by solving the related homework questions. Each assignment is due by the start of the next class. Late or no assignment submission is the grade's deduction point. |
| | 他学科聴講の可否
Propriety of Other department student's attendance | | | | 他学科聴講の条件
Conditions for Other department student's attendance | | | | レベル
Level | | | | キーワード
Keyword | | | | 履修の際のアドバイス
Advice | | | | 授業開講形態等
Lecture format, etc. | | | Face-to-face course（対面授業） |
| | 遠隔授業（オンデマンド型）で行う場合の追加措置
Additional measures for remote class (on-demand class) | | | |
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