授業の目的 【日本語】
Goals of the Course(JPN) | | |
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授業の目的 【英語】
Goals of the Course | | | This course offers an introduction to the fundamentals of molecular biophysics, where students will learn how to describe and analyze biological phenomena through the lens of physics. It covers key concepts that bridge biology and physics, helping students understand how physical principles, such as mechanics and thermodynamics apply to biological systems. By the end of the course, students will gain a deeper appreciation for the physical forces and interactions that govern biomolecules. |
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到達目標 【日本語】
Objectives of the Course(JPN) | | |
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到達目標【英語】
Objectives of the Course | | | This course will emphasize the crucial role of physics, chemistry, and computer science in understanding and studying biological molecules. Students will explore the physical and chemical principles underlying the behavior and structure of biological macromolecules, such as proteins. In addition, they acquire knowledge of key methods used to study these molecules, including experimental techniques and computational approaches. The course will also introduce students to computer tools for visualizing and analyzing protein structures and dynamics. By the end of the class, students will be equipped with a solid foundation in the interdisciplinary techniques essential for modern biophysical research. |
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授業の内容や構成
Course Content / Plan | | 1) Intro / What is Biophysics?
2) Water
3) Protein Structure
4) Protein Structure: Computer Exercise
5) Research Papers
6) Biophysical methods
7) Thermodynamics
8) Protein Stability & Folding
9) Protein Ligand interactions: Lecture + Computer Exercise
10) MD simulation
11) MD simulation: Computer Exercise
12) Evolution: Lecture + Computer Exercise
13) Presentation of research article by students |
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履修条件・関連する科目
Course Prerequisites and Related Courses | | |
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成績評価の方法と基準
Course Evaluation Method and Criteria | | | The final grade will be based on student presentations, assignments, and attendance. |
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教科書・テキスト
Textbook | | None is required.
Biochemistry textbooks might be helpful such as Lehninger’s Principles of Biochemistry. In addition, you may explore Protein Actions: Principles and Modeling, Introduction to Proteins: Structure, Function, and Motion. |
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参考書
Reference Book | | |
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課外学習等（授業時間外学習の指示）
Study Load(Self-directed Learning Outside Course Hours) | | | Students will have assignments. In addition, students will be requested to submit four reports. |
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使用言語
Language Used in the Course | | |
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授業開講形態等
Lecture format, etc. | | | Face-to-face course (Including some remote classes using simultaneous interactive and on-demand methods). A laptop is required for computer exercises. |
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遠隔授業（オンデマンド型）で行う場合の追加措置
Additional measures for remote class (on-demand class) | | |
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