授業の目的 【日本語】
Goals of the Course(JPN) | | | 本講座は、学生が主要概念を理解するための論理的枠組みを構築する手助けを目的として設置されました。学生は有機化合物とその誘導体について学び、特にヒドロキシル基、カルボニル基、エステル基、エーテル基、カルボン酸基、アミン基等といった重要な官能基について理解を深めます。さらに、有機化学反応性——具体的にはある官能基から別の官能基への変換——および関連する反応経路について明確な理解を得ることが目的です。[G30プログラム科目] |
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授業の目的 【英語】
Goals of the Course | | | The purpose of this course is to build a logical framework of organic chemistry and grasp the related principle knowledge. The course outlines typical reactions of organic compounds with specific functional groups, such as hydroxy, carbonyl, and amine groups, and their extended derivatives, such as acyl halides, esters, carboxylic acids, and amides. Students can indicate each chemical reaction that transforms one functional group into another and solve the progressive questions. |
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到達目標 【日本語】
Objectives of the Course(JPN)) | | | 本講座の主目的として、学生さんはヒドロキシル基、カルボニル基、エステル基、エーテル基、アミン基といった重要な官能基を含む有機化合物の化学反応と反応性、ならびにそれらの誘導体を学びます。学生さんは有機化学の基礎を理解するための論理的枠組みを習得し、最終的には様々な官能基の変換を伴う有機化学反応を理解し、その進行に関連する問題を解決できるようになります。[G30プログラム科目] |
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到達目標 【英語】
Objectives of the Course | | | The primary objective of this course is for students to learn the chemical reactions and reactivity of organic compounds containing critical functional groups, such as hydroxyl, ether, carbonyl, ester, carboxylic acid, and amine groups, as well as their derivatives. Students will acquire a logical framework for understanding the fundamentals of organic chemistry, ultimately gaining the ability to comprehend organic chemical reactions involving the transformation of various functional groups and to solve problems related to their progression. |
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バックグラウンドとなる科目【日本語】
Prerequisite Subjects | | |
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バックグラウンドとなる科目【英語】
Prerequisite Subjects | | | Fundamentals of Chemistry I and II and Organic Chemistry I and II |
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授業の内容【日本語】
Course Content | | |
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授業の内容【英語】
Course Content | | Class 1 & 2. Alcohols and Ethers --- Acidity/Basicity of Alcohols; Preparation of Alcohols (Nucleophilic Substitutions (SN1 & SN2), Reduction of Carbonyl Compounds, Hydrolysis of Esters); Reaction of Alcohols (Deprotonation, Substitution, Elimination, Oxidation, Inorganic Ester Formation); Preparation of Ethers (Williamson Ether Synthesis) and Reaction of Ethers.
Class 3. Esters --- Inorganic and Organic Esters; Haloalkane Formation from Alcohols via Inorganic Esters; Reaction of Organic Esters (Hydrolysis, Lactones into Open Chain Esters, Esters into Amides and Alcohols, Reduction).
Class 4. Acyl Halide --- Reactivity of Carbonyl Compounds (Leaving Ability of Leaving Groups); Reaction of Acyl Halides (Conversion into Carboxylic acid, Anhydride, Ester, Amide, Ketone, Aldehyde, and Phenylalkanone).
Class 5. Aldehydes and Ketones --- Preparations of Aldehydes and Ketones (Oxidation of Alcohols, Ozonolysis of Alkenes, Hydration of Alkynes; Friedel-Grafts Acylation)
Class 6. Reactions of Aldehydes and Ketones --- Grignard Reaction; Hydration (in acid/base); Acetalization/Deacetalization; Thioacetalization/Dethioacetalization/Desulfurization.
Class 7. Reactions of Aldehydes and Ketones --- Conversions into Cyanohydrin; Wittig Reaction; Baeyer-Villiger Oxidation; Conversion into Imine, Oxime, and Hydrazone; Reduction of Acyl Compounds into Alkanes.
Class 8. Assessment of Classes 1-7 with Practice Problems.
Class 9. Enols and Enolates --- Reactivity and Reaction Trends of Carbonyl Compounds in Acid and Base
Class 10. Reactivities of Formaldehyde, Aldehydes, and Ketones and Their Reactions --- Reactions with Amines (into Imine, Iminium, and Enamine) and Reaction Comparison; Mannich Reaction.
Class 11. Reactions of Conjugated Aldehydes, Ketones, --- Preparation of Conjugated Carbonyl Compounds; 1,2-addition versus 1,4-addition; Soft and Hard Base Nucleophiles; Michael Additions; Robinson Annulation.
Class 12. Carboxylic Acids --- Preparation of Carboxylic acids (Alcoholysis, Hydrolysis, Over-Oxidation of Primary Alcohols, Reduction of CO2, Conversion of Nitrile into Carboxylic Acid).
Class 13. Reactions of Carboxylic Acids --- Hell-Volhard-Zelinsky Bromination; Acyl Chloride Formation; Anhydride Formation; Decarboxylation.
Class 14. Intermolecular/Intramolecular Cross Condensations --- Aldol Condensation; Claisen Condensation; Retro-Claisen Condensation; Dieckmann Condensation.
Class 15. Assessment of Overall Classes (1-14) with Practice Problems. |
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成績評価の方法と基準【日本語】
Course Evaluation Method and Criteria | | |
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成績評価の方法と基準【英語】
Course Evaluation Method and Criteria | | ・Examination [total 70%: midterm (30%) and final (40%)] and Assignment of Homework and Attendances (30%): A+(≧95), A(95>x≧x80), B(80>x≧70), C(70>x≧65), C-(65>x≧60), and F(60＞x).
・There will be NO make-up exams in principle: It is essential to attend the exams during the scheduled class time.
・If the total score of the examinations [70%: midterm (30%) and final (40%)] and the assignment of homework and attendances (30%) is lower than 60, the student will receive an ‘F’ grade: i) Attendance is necessary for the successful completion of this course, and thus, absence will result in a reduction of points. ii) Students must submit each homework by the beginning of the next class, as it is vital for reviewing the corresponding lesson. Submitting homework late or not at all results in a point deduction.
・Submission of the "Course Withdrawal Request Form is necessary to withdraw from the course. The student needs to contact the course instructor to withdraw from the course. Failure to submit sickness/absence reports and to maintain attendance score will result in an 'F' grade. It is for the protection of other attendants in the corresponding course from the frequent absences of the specific/uncertain student(s). |
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履修条件・注意事項【日本語】
Course Prerequisites / Notes | | |
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履修条件・注意事項【英語】
Course Prerequisites / Notes | | ・The student should complete the prerequisite courses (Fundamentals of Chemistry I and II and Organic Chemistry I and II).
・This course strongly recommends that the student who wants to attend course lectures registers for the course properly. |
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教科書【日本語】
Textbook | | |
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教科書【英語】
Textbook | | | Organic Chemistry: Structure and Function (Eighth Edition), Peter K. Vollhardt and Neil Schore, (W. H. Freeman and Company), New York, 2018, Chapters 8-9, and 17-20. |
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参考書【日本語】
Reference Book | | |
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参考書【英語】
Reference Book | | | Organic Chemistry (eighth edition, Global edition), Paula Yurkanis Bruice (Pearson), 2017 ISBN 10: 1-292-16034-9, Chapters 10, 15-17. |
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授業時間外学習の指示【日本語】
Self-directed Learning Outside Course Hours | | |
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授業時間外学習の指示【英語】
Self-directed Learning Outside Course Hours | | ・Students are recommended to prepare each lecture by reading the corresponding chapters in the textbook and reviewing them by solving the related homework questions. NU general guidelines consider the necessity of an average of 2~3 hours of personal study time per credit.
・Students are recommended to review the lectures by solving the homework questions related to them. Each assignment is due at the start of the next class unless there is a special announcement. Late or missing assignment submissions result in a grade deduction.
・Participants can access lecture materials for each lesson via NUCT and check the schedules via the link.
・The course instructor may ask students pop-up questions during lectures to provide substantial feedback. |
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使用言語【英語】
Language used | | |
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使用言語【日本語】
Language used | | |
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授業開講形態等【日本語】
Lecture format, etc. | | |
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授業開講形態等【英語】
Lecture format, etc. | | |
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遠隔授業（オンデマンド型）で行う場合の追加措置【日本語】
Additional measures for remote class (on-demand class) | | |
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遠隔授業（オンデマンド型）で行う場合の追加措置【英語】
Additional measures for remote class (on-demand class) | | |
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実務経験のある教員等による授業科目（大学等における修学の支援に関する法律施行規則に基づくもの）＜実務経験について＞
Courses taught by Instructors with practical experience(Practical experience) | | |
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実務経験のある教員等による授業科目（大学等における修学の支援に関する法律施行規則に基づくもの）<実務経験と本授業との関連性>
Courses taught by Instructors with practical experience(Relevance of the practical experience to this course) | | |
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